Christiane Schotten

Christiane Schotten.jpg

Christiane graduated from RWTH Aachen University (Germany) where during her B.Sc. she conducted a final year research project with Prof. Palkovits. For her M.Sc. degree she carried out projects with Prof. Wessling, Prof. Liauw, Prof. Bolm and Prof. Leitner. During her MSc she also worked in a collaboration between Prof. Ley and Prof. Lapkin (University of Cambridge, UK) on a DAAD (German Academic Exchange Service) grant. During her PhD at Cardiff University (UK), Christiane worked with Dr Duncan Browne on multistep continuous flow processes using diazonium salts. She then carried out a project with Dr Timothy Noël at Eindhoven University of Technology (Netherlands) on an RSC Research Mobility Grant. Christiane joined the Willans group to work on a multifunctional electrochemical flow platform for high-throughput synthesis and optimisation of catalysts. 

Publications

  1. STEPHEN, H. R.; SCHOTTEN, C.; NICHOLLS, T. P.; WOODWARD, M.; BOURNE, R. A.; KAPUR, N.; WILLANS, C. E. A Versatile Electrochemical Batch Reactor for Synthetic Organic and Inorganic Transformations and Analytical Electrochemistry. Organic Process Research & Development, v. 24, 1084-1089, 2020.

  2. SCHOTTEN, C.; NICHOLLS, T. P.; BOURNE, R. A.; KAPUR, N.; NGUYEN, B. N.; WILLANS, C. E. Making electrochemistry easily accessible to the synthetic chemist. Green Chemistry, v. 22, p. 3358-3375, 2020.

  3. LAUDADIO, G.; BARMPOUTSIS, E.; SCHOTTEN, C.; STRUIK, L.; GOVAERTS, S.; BROWNE, D. L.; NOËL, T. Sulfonamide synthesis through electrochemical oxidative coupling of amines and thiols. Journal of the American Chemical Society, v. 141, p. 5664-5668, 2019.

  4. SCHOTTEN, C.; HOWARD, J. L.; JENKINS, R. L.; CODINA, A.; BROWNE, D. L. A continuous flow-batch hybrid reactor for commodity chemical synthesis enabled by inline NMR and temperature monitoring. Tetrahedron, v. 74, p. 5503-5509, 2018.

  5. SCHOTTEN, C.; LEIST, L. G. T.; SEMRAU, A. L.; BROWNE, D. L. A machine-assisted approach for the preparation of follow-on pharmaceutical compound libraries. Reaction Chemistry & Engineering, v. 3, p. 210-215, 2018.

  6. GROVES, L. M.; SCHOTTEN, C.; BEAMES, J.; PLATTS, J. A.; COLES, S. J.; HORTON, P. N.; BROWNE, D. L. POPE, S. J. A. From Ligand to Phosphor: Rapid, Machine-Assisted Syntheses of Substituted Iridium (III)-Pyrazolate Complexes with Tuneable Luminescence. Chemistry - A European Journal, v. 23, p. 9407-9418, 2017.

  7. HOWARD, J. L.; SAGATOV, Y.; REPUSSEAU, L.; SCHOTTEN, C.; BROWNE, D. L. Controlling reactivity through liquid assisted grinding: the curious case of mechanochemical fluorination. Green Chemistry, v. 19, p. 2798-2802, 2017.

  8. HOWARD, J. L.; SCHOTTEN, C.; BROWNE, D. L. Continuous flow synthesis of antimalarials: opportunities for distributed autonomous chemical manufacturing. Reaction Chemistry & Engineering, v. 2, p. 281-287, 2017.

  9. Browne DL; Howard JL; Schotten C (2017) Continuous Flow Processing as a Tool for Medicinal Chemical Synthesis. In: Chackalamannil S; Rotella S; Ward S eds. Comprehensive Medicinal Chemistry III, Vol. 1, Elsevier, pp. 135-185.

  10. SCHOTTEN, C.; ALDMAIRI, A. H.; SAGATOV, Y.; SHEPHERD, M.; BROWNE, D. L. A continuous-flow preparation of triazenes including the anticancer compounds dacarbazine and mitozolomide. Journal of Flow Chemistry, v. 6, p. 218-225, 2016.

  11. HOWARD, J. L.; SCHOTTEN, C.; ALSTON, S. T.; BROWNE, D. L. Preparation of difluoromethylthioethers through difluoromethylation of disulfides using TMS-CF2H. Chemical Communications, v. 52, p. 8448-8451, 2016.

  12. SCHOTTEN, C.; PLAZA, D.; MANZINI, S.; NOLAN, S.; LEY, S. V.; BROWNE, D. L.; LAPKIN, A. Continuous flow metathesis for direct valorization of food waste: an example of cocoa butter triglyceride. ACS Sustainable Chemistry & Engineering, v. 3, p. 1453-1459, 2015.

  13. WIERMANS, L.; HOFZUMAHAUS, S.; SCHOTTEN, C.; WEIGAND, L.; SCHALLMEY, M.; SCHALLMEY, A.; DOMINGUEZ DE MARIA, P. Transesterifications and Peracid-Assisted Oxidations in Aqueous Media Catalyzed by Mycobacterium smegmatis Acyl Transferase. ChemCatChem, v. 5, p. 3719-3724, 2013.